বুধবার, ১৫ আগস্ট, ২০১২

A little talk about Tuberculosis


  • Tuberculosis (TB) is an infection, primarily in the lungs (a pneumonia), caused by bacteria calledMycobacterium tuberculosis. It is spread usually from person to person by breathing infected air during close contact.
  • TB can remain in an inactive (dormant) state for years without causing symptoms or spreading to other people.
  • When the immune system of a patient with dormant TB is weakened, the TB can become active (reactivate) and cause infection in the lungs or other parts of the body.
  • The risk factors for acquiring TB include close-contact situations, alcohol and IV drug abuse, and certain diseases (for example, diabetes, cancer, and HIV) and occupations (for example, health-care workers).
  • The most common symptoms and signs of TB are fatiguefeverweight losscoughing, and night sweats.
  • The diagnosis of TB involves skin testschest X-rays, sputum analysis (smear and culture), and PCRtests to detect the genetic material of the causative bacteria.
  • Inactive tuberculosis may be treated with an antibiotic, isoniazid (INH), to prevent the TB infection from becoming active.
  • Active TB is treated, usually successfully, with INH in combination with one or more of several drugs, including rifampin (Rifadin), ethambutol (Myambutol), pyrazinamide, and streptomycin.
  • Drug-resistant TB is a serious, as yet unsolved, public-health problem, especially in Southeast Asia, the countries of the former Soviet Union, Africa, and in prison populations. Poor patient compliance, lack of detection of resistant strains, and unavailable therapy are key reasons for the development of drug-resistant TB.
  • The occurrence of HIV has been responsible for an increased frequency of tuberculosis. Control of HIV in the future, however, should substantially decrease the frequency of TB.

Candida


Candida is a genus of yeasts. Many species are harmless commensals or endosymbionts of hosts including humans, but other species, or harmless species in the wrong location, can cause disease. Candida albicanscan cause infections (candidiasis or thrush) in humans and other animals, especially in immunocompromisedpatients. In winemaking, some species of Candida can create potential faults in wines.

Laboratory characteristics: Grown in the laboratory, Candida appears as large, round, white or cream (albicans is from Latin meaning 'whitish') colonies with a yeasty odor on agar plates at room temperature. C. albicans ferments glucose and maltose to acid and gas, sucrose to acid, and does not ferment lactose, which help to distinguish it from other Candida species.

Clinical characteristics: Candida are almost universal on normal adult skin and albicans is part of the normal flora of the mucous membranes of the respiratory, gastrointestinal, and female genital tracts which cause no disease.
But overgrowth of several species including albicans can cause superficial infections such as oropharyngeal candidiasis (thrush) and vulvovaginal candidiasis (vaginal candidiasis). Oral candidiasis is common in elderly denture wearers. In otherwise healthy individuals, these infections can be cured with topical or systemic antifungal medications (commonly over-the-counter treatments like miconazole or clotrimazole). In debilitated or immunocompromised patients, or if introduced intravenously, candidiasis may become a systemic disease producing abscess, thrombophlebitis, endocarditis, or infections of the eyes or other organs. Colonization of the gastrointestinal tract by C. albicans after antibiotic therapy usually causes no symptoms and may also result from taking antacids or antihyperacidity drugs.
Candida symptoms: Once Candida proliferates in the body, it wrecks havoc in many ways and is the initiator of many common maladies, conditions, syndromes and illnesses in our population.
Some of the most frequent Candida symptoms are:
  • abdominal gas and bloating
  • headaches
  • migraines
  • excessive fatigue
  • cravings for alcohol
  • anxiety
  • vaginitis
  • rectal itching
  • cravings for sweets
  • inability to think clearly or concentrate
  • hyperactivity
  • mood swings
  • diarrhea
  • constipation
  • hyperactivity
  • itching
  • acne
  • eczema
  • depression
  • sinus inflammation
  • pre-menstrual syndrome
  • dizziness
  • poor memory
  • persistent cough
  • earaches
  • low sex drive
  • muscle weakness
  • irritability
  • learning difficulties
  • sensitivity to fragrances and/or other chemicals
  • cognitive impairment
  • thrush
  • athlete's foot
  • sore throat
  • indigestion
  • acid reflux
  • chronic pain
The brain is the organ that is most frequently affected by Candida Symptoms, but it also has profound negative effects on these systems:
  • digestive
  • nervous
  • cardiovascular
  • respiratory
  • reproductive
  • urinary
  • endocrine
  • lymphatic
  • musculoskeletal
Candida symptoms can vary from one person to another and often move back and forth between systems within the same individual.  One day you may experience symptoms in the musculoskeletal system and the next day it could be the digestive system ,etc.

Alternative medicine therapies: Many practitioners of alternative medicine use the term Candida to refer to a complex with broad spectrum of symptoms, the majority of which center around gastrointestinal distress, rashes, sore gums and other miscellaneous symptoms. Candida is accorded responsibility for symptoms as specific as hay fever, as vague as "brain fog" and as common as weight gain or flatulence. These symptoms are attributed by some alternative medicine practitioners to the "overgrowth" of intestinal Candida albicans, which they claim leads to the spread of the yeast to other parts of the body via the digestive tract and bloodstream.
Use of the term Candida in alternative medicine to describe this complex is unassociated with its use in clinical medicine to refer to the fungus that causes vaginal yeast infections and thrush. This can be confusing for patients. No studies have proven that having intestinal candidiasis causes any symptoms of illness.
To treat what they refer to as Candida, some alternative medicine practitioners have recommended avoiding antibiotics, birth control pills, and foods that are high in sugar or yeast, ostensibly to "eliminate excess yeast" in the body. However, there is little clinically valid evidence that these "Candida cleanse" treatments treat intestinal candidiasis effectively, or cure any of the symptoms claimed by the proponents of the hypothesis.
The probiotic Saccharomyces boulardii has been shown to diminish levels of intestinal Candida in mice. This is therefore one of the specific probiotic strains often recommended by alternative medicine practitioners alongside a more general probiotic, for anyone on a "Candida cleanse" or "Candida diet".

বুধবার, ১ আগস্ট, ২০১২

Surprising Health Benefits of Sex


Sexual Health

When you're in the mood, it's a sure bet that the last thing on your mind is boosting your immune system or maintaining a healthy weight. Yet good sex offers those health benefits and more. That's a surprise to many people, says Joy Davidson, PhD, a New York psychologist and sex therapist. "Of course, sex is everywhere in the media," she says. "But the idea that we are vital, sexual creatures is still looked at in some cases with disgust or in other cases a bit of embarrassment. So to really take a look at how our sexuality adds to our life and enhances our life and our health, both physical and psychological, is eye-opening for many people."
Sex does a body good in a number of ways, according to Davidson and other experts. The benefits aren't just anecdotal or hearsay -- each of these health benefits of sex is backed by scientific scrutiny.
There are many surprising health benefits of sex such as relieving stress, boosting your immunity, and more.

Sex Relieves Stress

A big health benefit of sex is lower blood pressure and overall stress reduction, according to researchers from Scotland who reported their findings in the journal Biological Psychology. They studied 24 women and 22 men who kept records of their sexual activity. Then the researchers subjected them to stressful situations -- such as speaking in public and doing verbal arithmetic -- and noted their blood pressure response to stress. Those who had intercourse had better responses to stress than those who engaged in other sexual behaviors or abstained.
One of the benefits of sex is stress release.

Sex Lowers Blood Pressure

Another study published in Biological Psychology found that frequent intercourse was associated with lower diastolic blood pressure (the lower, or second, number in a blood pressure reading). This study focused on people living with their sex partner.
Still further research found a link between partner hugs and lower blood pressure in women.
Elevated blood pressure is a risk factor for coronary artery disease, heart attack, kidney disease, and stroke
Sexual intercourse has been associated with lowering diastolic blood pressure.

Sex Boosts Immunity

Good sexual health may mean better physical health. Having sex once or twice a week has been linked with higher levels of an antibody called immunoglobulin A or IgA, which can protect you from getting colds and other infections. Scientists at Wilkes University in Wilkes-Barre, Pa., took samples of saliva, which contain IgA, from 112 college students who reported the frequency of sex they had.
Those in the "frequent" group -- once or twice a week -- had higher levels of IgA than those in the other three groups -- who reported being abstinent, having sex less than once a week, or having it very often, three or more times weekly.
Sex can help boost the immune system.

Sex Counts As Exercise

"Sex is a great mode of exercise," says Patti Britton, PhD, a Los Angeles sexologist and president of the American Association of Sexuality Educators and Therapists. It takes work, from both a physical and psychological perspective, to do it well, she says.
The benefits of sex as a form of exercise are many - sex can improve your cardiovascular fitness, strength, flexibility, and balance, not to mention your emotional health.
http://images.medicinenet.com/images/SlideShow/10-surprising-health-benefits-of-sex-s4-fit-couple.jpg

Sex Burns Calories

Thirty minutes of sex burns 85 calories or more. It may not sound like much, but it adds up: 42 half-hour sessions will burn 3,570 calories, more than enough to lose a pound. The number of calories burned during sex is about the same as the number burned by walking at 2 miles per hour.
Doubling up on the 30 minute sessions, you could drop that pound in 21 hour-long sessions.
Sex burns calories and helps lose pounds.

Sex Improves Cardiovascular Health

While some older folks may worry that the efforts expended during sex could cause a stroke, that's not so, according to researchers from England. In a study published in the Journal of Epidemiology and Community Health, scientists found that the frequency of sex was not associated with stroke in the 914 men they followed for 20 years.
And the heart health benefits of sex don't end there. The researchers also found that having sex twice or more a week reduced the risk of fatal heart attack by half for the men, compared with those who had sex less than once a month.
Sex is good for your heart health.

Archives of Sexual Behavior.
That finding makes sense to Gina Ogden, PhD, a sex therapist and marriage and family therapist in Cambridge, Mass., although she finds that those who already have self-esteem say they sometimes have sex to feel even better. "One of the reasons people say they have sex is to feel good about themselves," she tells WebMD. "Great sex begins with self-esteem, and it raises it. If the sex is loving, connected, and what you want, it raises it."
Sex can raise your self-esteem.

Sex Strengthens Your Well-Being

Sex, like any activity that fosters a close and loving connection to your partner, not only raises self-esteem, but strengthens your overall sense of well-being. Studies have shown that people with strong social support networks (which includes lovers) are healthier and happier than their less-connected peers.
Sex strengthens your overall sense of well-being.

Sex Improves Intimacy

Having sex and orgasms increases levels of the hormone oxytocin, the so-called love hormone, which helps us bond and build trust. Researchers from the University of Pittsburgh and the University of North Carolina evaluated 59 premenopausal women before and after warm contact with their husbands and partners ending with hugs. They found that the more contact, the higher the oxytocin levels.
"Oxytocin allows us to feel the urge to nurture and to bond," Britton says.
Higher oxytocin has also been linked with a feeling of generosity. So if you're feeling suddenly more generous toward your partner than usual, credit the love hormone.
Sex improves intimacy with your partner.

Sex Reduces Pain

As the hormone oxytocin surges, endorphins increase, and pain declines. So if your headache, arthritis pain, or PMS symptoms seem to improve after sex, you can thank those higher oxytocin levels.
Sex can help reduce the pain from conditions like headaches, arthritis, and more.

Oxytocin – The Love Hormone

A study published in the Bulletin of Experimental Biology and Medicine examined the response of the “love hormone” oxytocin on pain perception in an experiment with 48 volunteers. Study participants inhaled oxytocin vapor and then had their fingers pricked. Those who had inhaled oxytocin lowered their pain threshold by more than half.
Oxytocin or the love hormone can lower pain perception.

Sex Reduces Prostate Cancer Risk

Frequent ejaculations, especially in 20-something men, may reduce the risk of prostate cancer later in life, Australian researchers reported in the British Journal of Urology International. When they followed men diagnosed with prostate cancer and those without, they found no association of prostate cancer with the number of sexual partners as the men reached their 30s, 40s, and 50s.
But they found men who had five or more ejaculations weekly while in their 20s reduced their risk of getting prostate cancer later by a third.
Another study, reported in the Journal of the American Medical Association, found that frequent ejaculations, 21 or more a month, were linked to lower prostate cancer risk in older men, as well, compared with less frequent ejaculations of four to seven monthly.
Frequent ejaculations may reduce the risk of prostate cancer.

Sex Strengthens Pelvic Floor Muscles

For women, doing a few pelvic floor muscle exercises known as Kegel exercises during sex offers a couple of benefits. You will enjoy more pleasure, and you'll also strengthen the area and help to minimize the risk of incontinence later in life.
To do a basic Kegel exercise, tighten the muscles of your pelvic floor, as if you're trying to stop the flow of urine. Count to three, then release.
Kegel exercises improve pelvic floor muscles in women, which makes sex more pleasurable.

Additional Benefits of Kegel Exercises

Kegel exercises have a number of proven health benefits in addition to making sex more enjoyable. The strengthening of the pelvic floor muscles can help prevent prolapse (a slipping out of position) of the vagina, uterus, and bladder. Pelvic floor muscles may be weakened later in life as a result of childbearing, being overweight, and aging. Kegel exercises help offset the consequences of weakened pelvic floor muscles.
Kegel exercises have a number of proven health benefits in addition to making sex more enjoyable.

Sex Helps You Sleep Better

The oxytocin released during orgasm also promotes sleep, according to research.
And getting enough sleep has been linked with a host of other good things, such as maintaining a healthy weight and blood pressure. Something to think about, especially if you've been wondering why your guy can be active one minute and snoring the next.
Sex helps promote better sleep.

Sex As Physical Exercise Also Promotes Sleep

The physical exercise component of sex can also help you relax and sleep better, in addition to the hormonal effects. People who get regular exercise tend to sleep better and have more restful sleep. Moreover, as we have seen in the earlier part of this slideshow, sex is a great way to get some exercise.
The physical exercise component of sex can also help you relax and sleep better.

Summary

Take note that sex is good for you in ways you may never have imagined and that the health benefits extend well beyond the bedroom.
Take note that sex is good for you in ways you may never have imagined and that the health benefits extend well beyond the bedroom.




















A little talk about Pneumonia Part 4


What is the prognosis of pneumonia?

Pneumonia can be a serious and life-threatening infection. This is true especially in the elderly, children, and those who have other serious medical problems, such as COPD, heart disease, diabetes, and certain cancers. Fortunately, with the discovery of many potent antibiotics, most cases of pneumonia can be successfully treated. In fact, pneumonia can usually be treated with oral antibiotics without the need for hospitalization.

REFERENCES:

Hoare, Zara, and Wei Shen Lim. "Pneumonia: Update on Diagnosis and Management." BMJ 332 May 6, 2006: 1077-1079.

Meijvis, Sabine CA, et al. "Dexamethasone and Length of Hospital Stay in Patients With Community-Acquired Pneumonia: A Randomised, Double-Blind, Placebo-Controlled Trial." The Lancet. June 1, 2011. doi:10.1016/S0140-6736(11)60607-7.

United States. Centers for Disease Control and Prevention. "Seasonal Influenza (Flu)." June 3, 2011. <http://www.cdc.gov/flu/weekly/>.

A little talk about Pneumonia Part 3


What are some of the organisms that cause pneumonia? What is the treatment for pneumonia? Can pneumonia be prevented?

The most common cause of a bacterial pneumonia is Streptococcus pneumoniae. In this form of pneumonia, there is usually an abrupt onset of the illness with shaking chills, fever, and production of a rust-colored sputum. The infection spreads into the blood in 20%-30% of cases (known as sepsis), and if this occurs, 20%-30% of these patients die.
Two vaccines are available to prevent pneumococcal disease: the pneumococcal conjugate vaccine (PCV13) and the pneumococcal polysaccharide vaccine (PPV23; Pneumovax). The pneumococcal conjugate vaccine is part of the routine infant immunization schedule in the U.S. and is recommended for all children < 2 years of age and children 2-4 years of age who have certain medical conditions. The pneumococcal polysaccharide vaccine is recommended for adults at increased risk for developing pneumococcal pneumonia including the elderly, people who have diabetes, chronic heart, lung, or kidney disease, those with alcoholism, cigarette smokers, and in those people who have had their spleen removed. This vaccination should be repeated every five to seven years, whereas the flu vaccine is given annually.
Antibiotics often used in the treatment of this type of pneumonia include penicillin, amoxicillin and clavulanic acid (Augmentin, Augmentin XR), and macrolide antibiotics including erythromycin (E-Mycin, Eryc, Ery-Tab, PCE, Pediazole, Ilosone), azithromycin (Zithromax, Z-Max), and clarithromycin (Biaxin). Penicillin was formerly the antibiotic of choice in treating this infection. With the advent and widespread use of broader-spectrum antibiotics, significant drug resistance has developed. Penicillin may still be effective in treatment of pneumococcal pneumonia, but it should only be used after cultures of the bacteria confirm their sensitivity to this antibiotic.
Klebsiella pneumoniae and Hemophilus influenzae are bacteria that often cause pneumonia in people suffering from chronic obstructive pulmonary disease (COPD) or alcoholism. Useful antibiotics in this case are the second- and third-generation cephalosporins, amoxicillin and clavulanic acid, fluoroquinolones (levofloxacin [Levaquin], moxifloxacin-oral [Avelox], and sulfamethoxazole/trimethoprim [Bactrim, Septra]).
Mycoplasma pneumoniae is a type of bacteria that often causes a slowly developing infection. Symptoms include fever, chills, muscle aches, diarrhea, and rash. This bacterium is the principal cause of many pneumonias in the summer and fall months, and the condition often referred to as "atypical pneumonia." Macrolides (erythromycin, clarithromycin, azithromycin, and fluoroquinolones) are antibiotics commonly prescribed to treat Mycoplasma pneumonia.
Legionnaire's disease is caused by the bacterium Legionella pneumoniae that is most often found in contaminated water supplies and air conditioners. It is a potentially fatal infection if not accurately diagnosed. Pneumonia is part of the overall infection, and symptoms include high fever, a relatively slow heart rate, diarrhea, nausea, vomiting, and chest pain. Older men, smokers, and people whose immune systems are suppressed are at higher risk of developing Legionnaire's disease. Fluoroquinolones (see above) are the treatment of choice in this infection. This infection is often diagnosed by a special urine test looking for specific antibodies to the specific organism.
Mycoplasma, Legionnaire's, and another infection, Chlamydia pneumoniae, all cause a syndrome known as "atypical pneumonia." In this syndrome, the chest X-ray shows diffuse abnormalities, yet the patient does not appear severely ill. In the past, this condition was referred to as "walking pneumonia," a term that is rarely used today. These infections are very difficult to distinguish clinically and often require laboratory evidence for confirmation.
Recently, a study performed in the Netherlands demonstrated that adding a steroid medication, dexamethasone (Decadron), to antibiotic therapy shortens the duration of hospitalization. This medication should be used with caution in patients whom are critically ill or already have a compromised immune system.
Pneumocystis carinii (now known as Pneumocystis jiroveci) pneumonia is another form of pneumonia that usually involves both lungs. It is seen in patients with a compromised immune system, either from chemotherapy for cancer, HIV/AIDS, and those treated with TNF (tumor necrosis factor), such as for rheumatoid arthritis. Once diagnosed, it usually responds well to sulfa-containing antibiotics. Steroids are often additionally used in more severe cases.
Viral pneumonias do not typically respond to antibiotic treatment. These infections can be caused by adenoviruses, rhinovirus, influenza virus (flu), respiratory syncytial virus (RSV), and parainfluenza virus (that also causes croup). These pneumonias usually resolve over time with the body's immune system fighting off the infection. It is important to make sure that a bacterial pneumonia does not secondarily develop. If it does, then the bacterial pneumonia is treated with appropriate antibiotics. In some situations, antiviral therapy is helpful in treating these conditions. More recently, H1N1, swine-origin influenza A, has been associated with very severe pneumonia often resulting in respiratory failure. This disease often requires the use of mechanical ventilation for breathing support. Death is not uncommon when this infection involves the lungs.
Fungal infections that can lead to pneumonia include histoplasmosis, coccidiomycosis, blastomycosis, aspergillosis, and cryptococcosis. These are responsible for a relatively small percentage of pneumonias in the United States. Each fungus has specific antibiotic treatments, among which are amphotericin B, fluconazole (Diflucan), penicillin, and sulfonamides.
Major concerns have developed in the medical community regarding the overuse of antibiotics. Most sore throats and upper respiratory infections are caused by viruses rather than bacteria. Though antibiotics are ineffective against viruses, they are often prescribed. This excessive use has resulted in a variety of bacteria that have become resistant to many antibiotics. These resistant organisms are commonly seen in hospitals and nursing homes. In fact, physicians must consider the location when prescribing antibiotics (community-acquired pneumonia, or CAP, versus hospital-acquired pneumonia, or HAP).
The more virulent organisms often come from the health-care environment, either the hospital or nursing homes. These organisms have been exposed to a variety of the strongest antibiotics that we have available. They tend to develop resistance to some of these antibiotics. These organisms are referred to as nosocomial bacteria and can cause what is known as nosocomial pneumonia when the lungs become infected.
Recently, one of these resistant organisms from the hospital has become quite common in the community. In some communities, up to 50% of Staph aureus infections are due to organisms resistant to the antibiotic methicillin. This organism is referred to as MRSA (methicillin-resistant Staph aureus) and requires special antibiotics when it causes infection. It can cause pneumonia but also frequently causes skin infections. In many hospitals, patients with this infection are placed in contact isolation. Their visitors are often asked to wear gloves, masks, and gowns. This is done to help prevent the spread of this bacteria to other surfaces where they can inadvertently contaminate whatever touches that surface. It is therefore very important to wash your hands thoroughly and frequently to limit further spread of this resistant organism. The situation with MRSA continues to evolve. The community-acquired strain of MRSA tends to be responsive to some of the more commonly used antibiotics whereas the hospital-acquired strains require stronger, more aggressive antibiotic therapies. As this evolution occurs, patients are arriving in the hospital with the community-acquired strains as well as a previous hospital-acquired strain. This further necessitates performing bacterial cultures to determine the best course of action.

A little talk about Pneumonia Part 2


How is pneumonia diagnosed?

Pneumonia may be suspected when the doctor examines the patient and hears coarse breathing or crackling sounds when listening to a portion of the chest with a stethoscope. There may be wheezing or the sounds of breathing may be faint in a particular area of the chest. A chest X-ray is usually ordered to confirm the diagnosis of pneumonia. The lungs have several segments referred to as lobes, usually two on the left and three on the right. When the pneumonia affects one of these lobes, it is often referred to as lobar pneumonia. Some pneumonias have a more patchy distribution that does not involve specific lobes. In the past, when both lungs were involved in the infection, the term "double pneumonia" was used. This term is rarely used today.

Sputum samples can be collected and examined under the microscope. Pneumonia caused by bacteria or fungi can be detected by this examination. A sample of the sputum can be grown in special incubators, and the offending organism can be subsequently identified. It is important to understand that the sputum specimen must contain little saliva from the mouth and be delivered to the laboratory fairly quickly. Otherwise, overgrowth of noninfecting bacteria from the mouth may predominate. As we have used antibiotics in a broader uncontrolled fashion, more organisms are becoming resistant to the commonly used antibiotics. These types of cultures can help in directing more appropriate therapy.

A blood test that measures white blood cell count (WBC) may be performed. An individual's white blood cell count can often give a hint as to the severity of the pneumonia and whether it is caused by bacteria or a virus. An increased number of neutrophils, one type of WBC, is seen in most bacterial infections, whereas an increase in lymphocytes, another type of WBC, is seen in viral infections, fungal infections, and some bacterial infections (like tuberculosis).


Bronchoscopy is a procedure in which a thin, flexible, lighted viewing tube is inserted into the nose or mouth after a local anesthetic is administered. Using this device, the doctor can directly examine the breathing passages (trachea and bronchi). Simultaneously, samples of sputum or tissue from the infected part of the lung can be obtained.
Sometimes, fluid collects in the pleural space around the lung as a result of the inflammation from pneumonia. This fluid is called a pleural effusion. If a significant amount of fluid develops, it can be removed. After numbing the skin with local anesthetic a needle is inserted into the chest cavity and fluid can be withdrawn and examined under the microscope. This procedure is called a thoracentesis. Often ultrasound is used to prevent complications from this procedure. In some cases, this fluid can become severely inflamed (parapneumonic effusion) or infected (empyema) and may need to be removed by more aggressive surgical procedures. Today, most often, this involves surgery through a tube or thoracoscope. This is referred to as video-assisted thoracoscopic surgery or VATS.

A little talk about Pneumonia Part 1


Pneumonia facts
  • Pneumonia is a lung infection that can be caused by different types of microorganisms, including bacteria, viruses, and fungi.
  • Symptoms of pneumonia include cough with sputum production, fever, and sharp chest pain on inspiration (breathing in).
  • Pneumonia is suspected when a doctor hears abnormal sounds in the chest, and the diagnosis is confirmed by a chest X-ray.
  • Bacteria causing pneumonia can be identified by sputum culture.
  • A pleural effusion is a fluid collection around the inflamed lung.
  • Bacterial and fungal (but not viral) pneumonia can be treated with antibiotics.
What is pneumonia?
Pneumonia is an infection of one or both lungs which is usually caused by bacteria, viruses, or fungi. Prior to the discovery of antibiotics, one-third of all people who developed pneumonia subsequently died from the infection. Currently, over 3 million people develop pneumonia each year in the United States. Over a half a million of these people are admitted to a hospital for treatment. Although most of these people recover, approximately 5% will die from pneumonia. Pneumonia is the sixth leading cause of death in the United States.
How do people "catch pneumonia"?
Some cases of pneumonia are contracted by breathing in small droplets that contain the organisms that can cause pneumonia. These droplets get into the air when a person infected with these germs coughs or sneezes. In other cases, pneumonia is caused when bacteria or viruses that are normally present in the mouth, throat, or nose inadvertently enter the lung. During sleep, it is quite common for people to aspirate secretions from the mouth, throat, or nose. Normally, the body's reflex response (coughing back up the secretions) and their immune system will prevent the aspirated organisms from causing pneumonia. However, if a person is in a weakened condition from another illness, a severe pneumonia can develop. People with recent viral infections, lung disease, heart disease, and swallowing problems, as well as alcoholics, drug users, and those who have suffered a stroke or seizure are at higher risk for developing pneumonia than the general population. As we age, our swallowing mechanism can become impaired as does our immune system. These factors, along with some of the negative side effects of medications, increase the risk for pneumonia in the elderly.
Once organisms enter the lungs, they usually settle in the air sacs and passages of the lung where they rapidly grow in number. This area of the lung then becomes filled with fluid and pus (the body's inflammatory cells) as the body attempts to fight off the infection.
What are pneumonia symptoms and signs?
Most people who develop pneumonia initially have symptoms of a cold (upper respiratory infection, for example, sneezing, sore throat, cough), which are then followed by a high fever (sometimes as high as 104 F), shaking chills, and a cough with sputum production. The sputum is usually discolored and sometimes bloody. Depending on the location of the infection, certain symptoms are more likely to develop. When the infection settles in the air passages, cough and sputum tend to predominate the symptoms. In some, the spongy tissue of the lungs that contain the air sacs is more involved. In this case, oxygenation of the blood can be impaired, along with stiffening of the lung, which results in shortness of breath. At times, the individual's skin color may change and become dusky or purplish (a condition known as "cyanosis") due to their blood being poorly oxygenated.
The only pain fibers in the lung are on the surface of the lung, in the area known as the pleura. Chest pain may develop if the outer aspects of the lung close to the pleura are involved in the infection. This pain is usually sharp and worsens when taking a deep breath and is known as pleuritic pain or pleurisy. In other cases of pneumonia, depending on the causative organism, there can be a slow onset of symptoms. A worsening cough, headaches, and muscle aches may be the only symptoms.
Children and babies who develop pneumonia often do not have any specific signs of a chest infection but develop a fever, appear quite ill, and can become lethargic. Elderly people may also have few symptoms with pneumonia.